Beginning a Family: The different kinds of IVF

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Introduction

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We review the current methods used in In Vitro Fertilisation, and where future developments are taking the industry.

Intrauterine Insemination (IUI)

IUI is the process of injecting sperm that has been prepared by the partner’s male into the female’s womb at the time of ovulation.

Dr. Wingfield said “you keep an eye on the woman. When she’s pregnant, you ask the male to create a sperm specimen and then prepare it at the lab to pick the most fertile sperm and then inject the sperm in the uterus of the woman”. However, the rate of success for IUI has been described as “low” and “everything has to be normal. The woman needs to be having a follicle, her pelvis needs to be normal and her fallopian tubes have to be functioning normally, and the sperm must be normal, or slightly less than.”

In general, IUI has a rate of success of around 12 percent per try.

 

In Vitro Fertilisation (IVF)

The initial IVF child, Louise Brown, was born in the year 1978. Since then, more than 5 million IVF baby babies were born all over the world.

IVF is a series of crucial stages. It involves ovarian stimulation. women take fertility medications typically as daily injections, which stimulate their ovaries and produce many eggs. A woman then gets put under sedation and eggs are taken. The goal is to gather between 8 and 10 eggs. However, certain females will be more fertile eggs while some may have fewer. After the eggs have been collected, they are mixed up with laboratory sperm and then left to incubate hoping that the eggs will fertilize and develop into embryos. In the meantime, the woman uses other fertility medications to strengthen the wall of her womb to ensure that it is ready to take and accept the embryos that are born.

Fertilized

Around 50 percent of eggs are fertilized, and about half will grow to become embryos (a process that generally lasts between one and 5 days). After three, four, or even five days of gestation, the embryos will be transferred into the womb of the woman. It is up to each clinic to decide the number of embryos that are transferred, typically, it’s between one and two. Dr. Wingfield stated that the best method is to limit the number of embryos transferred to prevent the risk of multiple births (twins as well as triplets) that are extremely risky pregnancies. In exceptional circumstances (usually for older women) more than three embryos could be transferred. Additional embryos may be frozen for use in the future.

 

Intracytoplasmic Sperm Injection (ICSI)

ICSI is a form of IVF typically used in situations in which a male has an extremely low number of sperm or poor motility of the sperm. In standard IVF, around 100,000 sperm is injected into each egg and then placed in an incubator for a few hours, where it is hoped that only one sperm will be fertilized by each egg. In ICSI only one sperm can be injected into the egg. IVF in women who are younger than 35 has a rate of success of 50 to 60 percent, but it is vital to be aware of whether clinics are providing the probability of getting a pregnancy test positive or having a child (livebirth percentage).

Conclusion

Merrion Fertility Clinic’s total pregnancies rate (a pregnancy visible on Ultrasound scans) to be used for IVF also known as ICSI for 2014 was 53.2 percent for each complete cycle. However, the live birth rate varies from more than 50 percent in women younger than 35, to just 5 percent for women over 43.

 

When using IVF as well as ICSI, couples stand at a minimum of a one-in-3 chance of becoming pregnant and having a child. In the case of women who are younger than 35 and have a high success rate, it is about 50 percent. For women older than 42, the probability of having a child is one in 20 when it comes to IVF making use of eggs from her own.

However, the rate of success for IUI has been described as “low” and “everything has to be normal. The woman needs to be having a follicle, her pelvis needs to be normal and her fallopian tubes have to be functioning normally, and the sperm must be normal, or slightly less than.” it’s between one and two. Dr. Wingfield stated that the best method is to limit the number of embryos transferred to prevent the risk of multiple births (twins as well as triplets) that are extremely risky pregnancies. In exceptional circumstances (usually for older women) more than three embryos could be transferred. Additional embryos may be frozen for use in the future.